SCHEMBL8069267

SCHEMBL8069267

C=CCN1C[C@H](C)N([C@H](c2c[c]ccc2)c2cccc(C(=O)N(C)c3cccc(F)c3)c2)C[C@H]1C

nearest known ligand 0.81

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 1/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15080466 0.91 OPRD1 (0.88) OPRD1
SCHEMBL15061338 0.91 OPRD1 (0.88) OPRD1
SCHEMBL15061454 0.91 OPRD1 (0.88) OPRD1
SCHEMBL3579696 0.90 OPRD1 (1.00) OPRD1
SCHEMBL3579700 0.90 OPRD1 (1.00) OPRD1
SCHEMBL8930484 0.90 OPRD1 (1.00) OPRD1
SCHEMBL29406897 0.90 OPRD1 (1.00) OPRD1
SCHEMBL8078564 0.88 OPRD1 (0.81) OPRD1
SCHEMBL8081629 0.85 OPRD1 (0.77) OPRD1
SCHEMBL8930525 0.85 OPRD1 (0.77) OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0711289-B1 PIPERAZINE COMPOUNDS USED IN THERAPY DELTA PHARMACEUTICALS INC (US) 2000-08-23 EP claimed