Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30353880 | 1.00 | MEN1 (0.35) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL997888 | 0.81 | MEN1 (0.39) | MEN1KMT2AALOX12KDM4EALDH1A1 | |
| SCHEMBL4601117 | 0.74 | POLB (0.33) | MEN1KMT2AGAAMAOAMAOB | |
| SCHEMBL5077476 | 0.74 | CYP2A6 (0.39) | MEN1KMT2AALOX12KDM4EALDH1A1 | |
| SCHEMBL16346114 | 0.69 | TSHR (0.35) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL545454 | 0.67 | MEN1 (0.53) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL29490140 | 0.67 | MEN1 (0.53) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL29436947 | 0.67 | EDNRA (0.43) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL2210400 | 0.65 | MAOA (0.42) | MEN1KMT2AGAAHTR2AALOX12 | |
| SCHEMBL4822373 | 0.65 | HTR2A (0.42) | MEN1KMT2AGAAHTR2AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1012201-A1 | POLY(ARYL VINYLENE)S | White Knight Technologies Limited (GB) | 2000-06-28 | — | — | EP | disclosed |
| WO-1999014255-A1 | POLY(ARYL VINYLENE)S | WHITE KNIGHT TECHNOLOGIES LIMITED (GB) | 1999-03-25 | — | — | WO | disclosed |