Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072249 | 0.96 | MMP13 (0.66) | MMP13 | |
| SCHEMBL8076870 | 0.93 | MMP13 (0.61) | MMP13 | |
| SCHEMBL8071838 | 0.90 | MMP13 (0.69) | MMP13 | |
| SCHEMBL8067050 | 0.90 | MMP13 (0.75) | MMP13 | |
| SCHEMBL8070591 | 0.90 | MMP13 (0.81) | MMP13 | |
| SCHEMBL3803124 | 0.90 | MMP13 (0.60) | MMP13 | |
| SCHEMBL3803121 | 0.90 | MMP13 (0.60) | MMP13 | |
| SCHEMBL8071597 | 0.89 | MMP13 (0.72) | MMP13 | |
| SCHEMBL8071412 | 0.89 | MMP13 (0.74) | MMP13 | |
| SCHEMBL8056324 | 0.89 | MMP13 (0.70) | MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |