Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22723993 | 0.85 | BRD4 (0.50) | BRD4L3MBTL1GAAKDM4ETP53 | |
| SCHEMBL9394461 | 0.79 | BRD4 (0.51) | BRD4NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL926245 | 0.79 | BRD4 (0.74) | BRD4L3MBTL1KDM4EALDH1A1HPGD | |
| SCHEMBL30251521 | 0.79 | PTPN1 (0.61) | NR4A1NR4A2NR4A3KDM4EPTPN1 | |
| SCHEMBL1130987 | 0.79 | PTPN1 (0.61) | NR4A1NR4A2NR4A3KDM4EPTPN1 | |
| SCHEMBL15869662 | 0.78 | PARP1 (0.52) | BRD4NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL29406795 | 0.77 | NR4A1 (0.73) | L3MBTL1NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL27985 | 0.77 | NR4A1 (0.73) | L3MBTL1NR4A1NR4A2NR4A3KDM4E | |
| SCHEMBL8268239 | 0.77 | GAA (0.56) | BRD4L3MBTL1GAAKDM4ETP53 | |
| SCHEMBL2280624 | 0.76 | ALDH1A1 (0.46) | BRD4L3MBTL1NR4A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009044018-A2 | DERIVATIVES OF 1-OXO-1,2-DIHYDROISOQUINOLINE-5-CARBOXAMIDES AND OF 4-OXO-3,4-DIHYDROQUINAZOLINE-8-CARBOXAMIDES, PREPARATION THEREOF AND APPLICATION THEREOF IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2009-04-09 | — | — | WO | disclosed |