Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 10/20 | 0.60 |
| ▸ | PI4KA | P42356 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.42 |
| ▸ | MTOR | P42345 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.41 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.41 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.41 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.41 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.41 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789765 | 0.87 | PI4KA (0.61) | PIK3CGPI4KAALDH1A1POLBTSHR | |
| SCHEMBL790388 | 0.84 | PIK3CG (0.56) | PIK3CGPI4KAALDH1A1POLBTSHR | |
| SCHEMBL10274844 | 0.80 | PIK3CG (0.54) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL789570 | 0.75 | PIK3CG (1.00) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL790028 | 0.74 | PI4KA (0.60) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807206 | 0.73 | PIK3CG (0.86) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL791544 | 0.73 | PI4KA (0.64) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL9955053 | 0.73 | PI4KA (0.79) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL790386 | 0.73 | PIK3CG (0.82) | PIK3CGPI4KAPIK3CAMTORPIK3CD | |
| SCHEMBL807154 | 0.73 | PIK3CG (0.82) | PIK3CGPI4KAPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |