Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.56 |
| ▸ | PI4KA | P42356 | 9/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | MTOR | P42345 | 3/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL789765 | 0.85 | PI4KA (0.61) | PIK3CGPI4KAMEN1KMT2AALDH1A1 | |
| SCHEMBL806963 | 0.84 | PIK3CG (0.60) | PIK3CGPI4KAMEN1KMT2AALDH1A1 | |
| SCHEMBL790763 | 0.84 | PIK3CG (0.62) | PIK3CGPI4KAPIK3CAMTORSLC40A1 | |
| SCHEMBL790102 | 0.83 | PIK3CG (0.66) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL789337 | 0.82 | PIK3CG (0.77) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL807092 | 0.82 | PI4KA (0.55) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL790186 | 0.79 | PI4KA (0.53) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL790895 | 0.79 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1POLBTSHR | |
| SCHEMBL790869 | 0.78 | PI4KA (0.62) | PIK3CGPI4KAPIK3CAMTOR | |
| SCHEMBL9955053 | 0.78 | PI4KA (0.79) | PIK3CGPI4KAPIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |