Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 13/20 | 0.52 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069635 | 1.00 | CYP19A1 (0.52) | CYP19A1UGT1A4PDE4DESR1STS | |
| SCHEMBL8059033 | 0.72 | CYP19A1 (0.58) | CYP19A1UGT1A4PDE4DESR1STS | |
| SCHEMBL5319610 | 0.69 | CYP19A1 (0.46) | CYP19A1 | |
| Anastrozole SCHEMBL177942 | 0.69 | CYP19A1 (1.00) | CYP19A1UGT1A4PDE4DESR1STS | |
| Anastrozole SCHEMBL27927481 | 0.69 | CYP19A1 (1.00) | CYP19A1UGT1A4PDE4DESR1STS | |
| Anastrozole SCHEMBL9726 | 0.69 | CYP19A1 (1.00) | CYP19A1UGT1A4PDE4DESR1STS | |
| SCHEMBL5442996 | 0.69 | CYP19A1 (0.55) | CYP19A1UGT1A4PDE4DESR1 | |
| SCHEMBL13941093 | 0.69 | CYP19A1 (0.61) | CYP19A1UGT1A4PDE4DESR1STS | |
| SCHEMBL937134 | 0.68 | CYP19A1 (0.73) | CYP19A1UGT1A4PDE4DESR1STS | |
| SCHEMBL937133 | 0.68 | CYP19A1 (0.73) | CYP19A1UGT1A4PDE4DESR1STS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE36617-E | Anastrozole and salts as anticancer agent | ZENECA LIMITED (GB) | 2000-03-14 | — | — | US | disclosed |
| US-4935437-A | (Substituted aralkyl) heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-19 | — | — | US | disclosed |