Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17183193 | 0.88 | MAPT (0.50) | MAPTL3MBTL1MEN1KMT2ARECQL | |
| SCHEMBL15707033 | 0.88 | MAPT (0.50) | MAPTL3MBTL1MEN1KMT2ARECQL | |
| SCHEMBL4049521 | 0.85 | TDP1 (0.48) | MAPTMEN1KMT2APOLBNPSR1 | |
| SCHEMBL8590595 | 0.85 | MAPT (0.51) | MAPTL3MBTL1MEN1KMT2ARECQL | |
| SCHEMBL7418294 | 0.81 | FPR2 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL2467817 | 0.80 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL1491720 | 0.80 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL699636 | 0.80 | FOLH1 (0.65) | MAPTSYKKLK7KLK5FOLH1 | |
| SCHEMBL8117254 | 0.80 | HDAC3 (0.67) | MAPTKLK7KLK5HDAC3HDAC4 | |
| SCHEMBL5363018 | 0.80 | MAPT (0.60) | MAPTL3MBTL1MEN1KMT2ARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |