Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322477 | 0.80 | TSHR (0.53) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL93224 | 0.78 | — | — | |
| SCHEMBL3632057 | 0.76 | — | — | |
| SCHEMBL29654621 | 0.74 | LMNA (0.39) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL28773983 | 0.74 | LMNA (0.39) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL9716539 | 0.74 | LMNA (0.39) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL364390 | 0.73 | FFAR3 (0.38) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL271740 | 0.72 | — | — | |
| SCHEMBL10733232 | 0.71 | FFAR3 (0.35) | ALDH1A1TSHRFFAR3LCKFYN | |
| SCHEMBL28219606 | 0.71 | FFAR3 (0.35) | ALDH1A1TSHRFFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620857-B1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LTD (GB) | 2000-08-02 | — | — | EP | disclosed |
| US-5686275-A | LACTATE DEHYDROGENASE | GENZYME LTD. (GB) | 1997-11-11 | — | — | US | disclosed |
| EP-0620857-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | Genzyme Limited (GB) | 1994-10-26 | — | — | EP | disclosed |
| WO-1993013215-A1 | SYNTHESIS OF HOMOCHIRAL 2-HYDROXY ACIDS | GENZYME LIMITED (GB) | 1993-07-08 | — | — | WO | disclosed |