Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.52 |
| ▸ | GID4 | Q8IVV7 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.49 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29842306 | 0.84 | GID4 (0.62) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL395087 | 0.84 | GID4 (0.62) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL20863599 | 0.81 | HAO1 (0.53) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL20863578 | 0.81 | HAO1 (0.53) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL7059074 | 0.81 | HAO1 (0.57) | HAO1GID4MAPK1MAPK14TAOK1 | |
| SCHEMBL20874477 | 0.78 | GID4 (0.56) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL29155816 | 0.78 | GID4 (0.52) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL20856005 | 0.78 | HAO1 (0.53) | HAO1GID4MAPK1MAPK14ADRA2A | |
| SCHEMBL13444088 | 0.78 | GID4 (0.72) | HAO1GID4MAPK1MAPK14ALDH1A1 | |
| SCHEMBL7324670 | 0.78 | GID4 (0.72) | HAO1GID4MAPK1MAPK14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025177-A | ENANTIOSELECTIVE SYNTHESIS OF CHIRAL ALPHA-HYDROXYCARBOXYLATE BY REACTING A PROCHIRAL ALPHA-KETOCARBOXYLIC ACID WITH A SINGLE ENANTIOMER OF AN N-SUBSTITUTED VICINAL AMINOALCOHOL OF SPECIFIC CYCLOHYDROCARBONS TO FORM ALPHA-HYDROXYCARBOXYLATE | SEPRACOR INC. (US) | 2000-02-15 | — | — | US | disclosed |