Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | RXRG | P48443 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | BAD | Q92934 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CXCR5 | P32302 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | FABP4 | P15090 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068418 | 0.81 | MEN1 (0.41) | POLBMAPTALDH1A1MEN1LMNA | |
| SCHEMBL8074878 | 0.79 | KMT2A (0.41) | L3MBTL1POLBMAPTALDH1A1MEN1 | |
| SCHEMBL8059309 | 0.75 | KDM4E (0.32) | L3MBTL1POLBMAPTMCL1ALDH1A1 | |
| SCHEMBL8059334 | 0.73 | NLRP3 (0.31) | L3MBTL1POLBMAPTMCL1ALDH1A1 | |
| SCHEMBL8059336 | 0.72 | NLRP3 (0.30) | L3MBTL1POLBMCL1ALDH1A1MEN1 | |
| SCHEMBL5799161 | 0.69 | EGFR (0.41) | L3MBTL1MAPTTDP1MCL1ALDH1A1 | |
| SCHEMBL29493191 | 0.67 | CXCR5 (0.56) | L3MBTL1RXRARXRBRXRGBCL2L1 | |
| SCHEMBL783869 | 0.67 | CXCR5 (0.56) | L3MBTL1RXRARXRBRXRGBCL2L1 | |
| SCHEMBL5755502 | 0.65 | CXCR5 (0.55) | L3MBTL1RXRARXRBRXRGBCL2L1 | |
| Hydrochloric Acid SCHEMBL2398251 | 0.65 | CXCR5 (0.55) | L3MBTL1RXRARXRBRXRGBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0803501-B1 | Substituted guanidine derivatives and their use as Na+/H+ exchange inhibitors | SUMITOMO PHARMA (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0803501-A1 | Substituted guanidine derivatives and their use as Na+/H+ exchange inhibitors | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1997-10-29 | — | — | EP | disclosed |