Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10487984 | 1.00 | MEN1 (0.65) | MEN1KMT2AFDFT1CYP19A1SIGMAR1 | |
| SCHEMBL9136546 | 1.00 | MEN1 (0.65) | MEN1KMT2AFDFT1CYP19A1SIGMAR1 | |
| SCHEMBL13423741 | 1.00 | MEN1 (0.65) | MEN1KMT2AFDFT1CYP19A1SIGMAR1 | |
| SCHEMBL51135 | 0.98 | MEN1 (0.67) | MEN1KMT2AFDFT1CYP19A1MGLL | |
| SCHEMBL51024 | 0.92 | MEN1 (0.69) | MEN1KMT2ACYP19A1MGLLTAAR1 | |
| SCHEMBL9427165 | 0.87 | MEN1 (0.51) | MEN1KMT2AFDFT1CYP19A1SIGMAR1 | |
| SCHEMBL13423728 | 0.85 | MEN1 (0.53) | MEN1KMT2AFDFT1CYP19A1SIGMAR1 | |
| SCHEMBL24137898 | 0.84 | MEN1 (0.62) | MEN1KMT2ATAAR1SLC6A2SLC6A4 | |
| SCHEMBL52143 | 0.84 | MEN1 (0.62) | MEN1KMT2ATAAR1SLC6A2SLC6A4 | |
| SCHEMBL2077308 | 0.84 | MEN1 (0.62) | MEN1KMT2ATAAR1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121270-A | N-(EPOXYALKYL)XANTHINE DERIVATIVES WHICH MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI | CELL THERAPEUTICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |