SCHEMBL51024

SCHEMBL51024

c1ccc(CCCC2CO2)cc1

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.69
KMT2A Q03164 1/20 0.69
TAAR1 Q96RJ0 1/20 0.53
CYP19A1 P11511 1/20 0.44
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
SLC6A3 Q01959 1/20 0.44
MGLL Q99685 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51135 0.94 MEN1 (0.67) MEN1KMT2ATAAR1CYP19A1SLC6A2
SCHEMBL8070541 0.92 MEN1 (0.65) MEN1KMT2ATAAR1CYP19A1SLC6A2
SCHEMBL13423741 0.92 MEN1 (0.65) MEN1KMT2ATAAR1CYP19A1SLC6A2
SCHEMBL9136546 0.92 MEN1 (0.65) MEN1KMT2ATAAR1CYP19A1SLC6A2
SCHEMBL10487984 0.92 MEN1 (0.65) MEN1KMT2ATAAR1CYP19A1SLC6A2
SCHEMBL24137898 0.87 MEN1 (0.62) MEN1KMT2ATAAR1SLC6A2SLC6A4
SCHEMBL52143 0.87 MEN1 (0.62) MEN1KMT2ATAAR1SLC6A2SLC6A4
SCHEMBL2077308 0.87 MEN1 (0.62) MEN1KMT2ATAAR1SLC6A2SLC6A4
SCHEMBL19347555 0.80 ALOX5 (0.51) MEN1KMT2ATAAR1SLC6A2SLC6A4
SCHEMBL8802944 0.80 MEN1 (0.47) MEN1KMT2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104448451-A Thermoplastic elastomer composition YOKOHAMA RUBBER CO LTD 2015-03-25 CN claimed
CN-109535707-B Pneumatic tire 横滨橡胶株式会社 2021-05-25 CN disclosed
EP-2508342-B1 INNER LINER FOR PNEUMATIC TIRE, AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-04-01 EP disclosed
EP-2508343-B1 MULTILAYER STRUCTURE AND METHOD FOR PRODUCING SAME KURARAY CO (JP) 2020-03-11 EP disclosed
EP-2554372-B1 MULTILAYERED STRUCTURE AND LAMINATE AND METHOD FOR PRODUCTION OF THE SAME KURARAY CO (JP) 2020-01-08 EP disclosed
EP-2857451-B1 PNEUMATIC TIRE YOKOHAMA RUBBER CO LTD (JP) 2019-05-08 EP disclosed
CN-107116869-B Multilayer structure making, pneumatic tire inner liner and pneumatic tire 株式会社普利司通 2019-04-30 CN disclosed
EP-2623315-B1 MULTILAYERED STRUCTURE, INNER LINER HAVING THE SAME, AND PNEUMATIC TIRE KURARAY CO (JP) 2019-04-17 EP disclosed
EP-2716445-B1 MULTI-LAYERED STRUCTURE, INNER LINER FOR PNEUMATIC TIRE, AND PNEUMATIC TIRE BRIDGESTONE CORP (JP) 2019-04-10 EP disclosed
CN-109535707-A Pneumatic tire 横滨橡胶株式会社 2019-03-29 CN disclosed
EP-0540009-A1 Process for producing epoxides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-05-05 EP disclosed
US-4758573-A Heterocyclic group-containing compounds G. D. SEARLE & CO. (US) 1988-07-19 US disclosed
EP-0267439-A2 Alpha-(phenylalkyl) pyridinealkanol derivatives G.D. Searle & Co. (US) 1988-05-18 EP disclosed
EP-0105575-B1 1-(1H-IMIDAZOLYL), 1-N-MORPHOLINYL AND PYRIDYL COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM G.D. Searle & Co. (US) 1987-03-04 EP disclosed
US-4579862-A TREATMENT OF CEREBROVASCULAR DISEACE, ISCHEMIA, DIABETES, ANGINA, MYOCARDIAL INFARCTION G. D. SEARLE & CO. (US) 1986-04-01 US disclosed
EP-0105575-A1 1-(1H-imidazolyl), 1-N-morpholinyl and pyridyl compounds, their preparation and pharmaceutical compositions containing them G.D. Searle & Co. (US) 1984-04-18 EP disclosed
US-4186255-A POLYURETHANE CATALYST TEXACO DEVELOPMENT CORPORATION (US) 1980-01-29 US disclosed
US-4136240-A METALLIC QUATERNARY AMMONIUM CARBOXYLATES AS POLYISOCYANURATE CATALYSTS TEXACO DEVELOPMENT CORPORATION (US) 1979-01-23 US disclosed
US-4075130-A DIAMINES, TRIAMINES TEXACO DEVELOPMENT CORPORATION (US) 1978-02-21 US disclosed
US-4060501-A Novolak derivatives as defoamers TEXACO DEVELOPMENT CORPORATION (US) 1977-11-29 US disclosed