Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8075411 | 0.97 | TBXA2R (0.37) | TBXA2RNR1I2ADORA3DRD1AGTR1 | |
| SCHEMBL13311307 | 0.91 | SMYD2 (0.38) | TBXA2RNR1I2ADORA3DRD1AGTR1 | |
| SCHEMBL8070836 | 0.90 | SMN1; SMN2 (0.37) | TBXA2RNR1I2ADORA3DRD1AGTR1 | |
| SCHEMBL8071091 | 0.90 | SMN1; SMN2 (0.37) | TBXA2RNR1I2ADORA3DRD1AGTR1 | |
| SCHEMBL16520364 | 0.87 | SMYD2 (0.36) | TBXA2RNR1I2ADORA3DRD1AGTR1 | |
| SCHEMBL6345426 | 0.85 | PPARA (0.43) | TBXA2RHDAC1HDAC2PPARA | |
| SCHEMBL25355046 | 0.84 | TBXA2R (0.43) | TBXA2RHDAC1HDAC2PPARA | |
| SCHEMBL31528895 | 0.84 | TBXA2R (0.43) | TBXA2RHDAC1HDAC2PPARA | |
| SCHEMBL30887240 | 0.84 | TBXA2R (0.43) | TBXA2RHDAC1HDAC2PPARA | |
| SCHEMBL31528916 | 0.84 | TBXA2R (0.43) | TBXA2RHDAC1HDAC2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |