Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | SMYD2 | Q9NRG4 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | PTGIR | P43119 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071091 | 1.00 | SMN1; SMN2 (0.37) | SMN1; SMN2SMYD2CYP3A4HTTALOX15 | |
| SCHEMBL13311307 | 0.98 | SMYD2 (0.38) | SMN1; SMN2SMYD2CYP3A4HTTALOX15 | |
| SCHEMBL8070769 | 0.90 | TBXA2R (0.40) | SMN1; SMN2SMYD2CYP3A4HTTALOX15 | |
| SCHEMBL8075411 | 0.90 | TBXA2R (0.37) | SMN1; SMN2SMYD2CYP3A4HTTALOX15 | |
| SCHEMBL22557449 | 0.88 | LMNA (0.39) | SMN1; SMN2SMYD2CYP3A4HTTL3MBTL1 | |
| SCHEMBL2556825 | 0.88 | LMNA (0.39) | SMN1; SMN2SMYD2CYP3A4HTTL3MBTL1 | |
| SCHEMBL22557768 | 0.87 | SMN1; SMN2 (0.38) | SMN1; SMN2SMYD2CYP3A4HTTPOLB | |
| SCHEMBL15195469 | 0.85 | CYP3A4 (0.38) | SMN1; SMN2SMYD2CYP3A4HTTPTGIR | |
| SCHEMBL13250794 | 0.85 | SMYD2 (0.37) | SMN1; SMN2SMYD2CYP3A4HTTKMT2A | |
| SCHEMBL20475256 | 0.85 | SMYD2 (0.37) | SMN1; SMN2SMYD2CYP3A4HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080771-A | LEINAMYCIN DERIVATIVES ARE USED AS BACTERICIDE AND ANTITUMOR AGENTS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2000-06-27 | — | — | US | disclosed |
| EP-0887351-A1 | DC 107 DERIVATIVES (2) | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-30 | — | — | EP | disclosed |