Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.45 |
| ▸ | TUBB | P07437 | 2/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3466908 | 0.84 | TSHR (0.54) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL3791466 | 0.83 | MGAM (0.53) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL3787842 | 0.83 | AKR1C3 (0.52) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL3787713 | 0.82 | AKR1C3 (0.60) | AKR1C3AKR1C2MAPTMEN1ALDH1A1 | |
| SCHEMBL16710319 | 0.81 | AKR1C3 (0.62) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL3466403 | 0.80 | PDE4D (0.49) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL4321641 | 0.80 | PDE4D (0.49) | AKR1C3AKR1C2TDP1PDE4DPDE4B | |
| SCHEMBL16712925 | 0.79 | ALDH1A1 (0.57) | AKR1C3AKR1C2MAPTMEN1ALDH1A1 | |
| SCHEMBL7615616 | 0.79 | PDE4B (0.56) | AKR1C3AKR1C2PDE4DPDE4BMAPT | |
| SCHEMBL29408235 | 0.78 | PTGDR2 (0.63) | TDP1MAPTMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009067600-A2 | BIARYL PDE4 INHIBITORS FOR TREATING INFLAMMATION | DECODE GENETICS EHF (IS) | 2009-05-28 | — | — | WO | disclosed |