Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.59 |
| ▸ | CTSK | P43235 | 8/20 | 0.59 |
| ▸ | CTSB | P07858 | 7/20 | 0.59 |
| ▸ | CTSL | P07711 | 5/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | SYK | P43405 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | AKT1 | P31749 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19837597 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL18154315 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL11123304 | 0.90 | CTSS (0.69) | CTSSCTSKCTSBCTSLPPARA | |
| SCHEMBL8072132 | 0.87 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL8072127 | 0.87 | ACE (0.60) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10054705 | 0.86 | ACE (0.59) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL10054782 | 0.86 | ACE (0.59) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL30100566 | 0.84 | CTSS (0.63) | CTSSCTSKCTSBCTSLACE | |
| SCHEMBL11120671 | 0.84 | CTSS (0.66) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL30100571 | 0.84 | CTSS (0.58) | CTSSCTSKCTSBCTSLACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080838-A | SYNTHETIC CONSTRUCT PREPARED TO HOLD TWO PEPTIDE HELICES IN TIGHT ARRANGEMENT TO MIMIC DNA BINDING CONFORMATION; FOR INVESSTIGATIONAL STUDIES | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2000-06-27 | — | — | US | disclosed |