Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | BLM | P54132 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | WDR5 | P61964 | 3/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | BRS3 | P32247 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | DDAH1 | O94760 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23988288 | 0.85 | KMT2A (0.41) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23988511 | 0.85 | KMT2A (0.41) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL23988289 | 0.85 | KMT2A (0.41) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL8069090 | 0.84 | FGFR1 (0.42) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL2615442 | 0.83 | KMT2A (0.44) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4548502 | 0.83 | KMT2A (0.44) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL15032050 | 0.83 | KMT2A (0.44) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| Omeprazole SCHEMBL82985 | 0.82 | BRS3 (0.52) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| Omeprazole SCHEMBL1560726 | 0.82 | BRS3 (0.52) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT | |
| Omeprazole SCHEMBL1191 | 0.82 | BRS3 (0.52) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | claimed |
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |