Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.41 |
| ▸ | BRS3 | P32247 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | WDR5 | P61964 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.35 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.35 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.35 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.35 |
| ▸ | ATP4A | P20648 | 2/20 | 0.35 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.35 |
| ▸ | ATP4B | P51164 | 2/20 | 0.35 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.35 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.35 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8060015 | 0.92 | PDE10A (0.40) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL8075658 | 0.87 | HTT (0.39) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL8070889 | 0.84 | KMT2A (0.42) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL8059870 | 0.82 | BRS3 (0.36) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL8061857 | 0.81 | OPRL1 (0.60) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL12439146 | 0.79 | BRS3 (0.41) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL8059765 | 0.79 | OPRL1 (0.41) | FGFR1FGFR2FGFR3KDROPRL1 | |
| SCHEMBL13285214 | 0.78 | KMT2A (0.42) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL2631548 | 0.78 | KMT2A (0.42) | BRS3KMT2AWDR5CYP2C9ATP1A1 | |
| SCHEMBL8073957 | 0.78 | ATP4A (0.42) | FGFR1FGFR2FGFR3KDROPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | claimed |
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |