Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.69 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071400 | 0.92 | MMP13 (0.75) | MMP13SLC22A8MMP3 | |
| SCHEMBL8069505 | 0.92 | MMP13 (0.75) | MMP13SLC22A8MMP3 | |
| SCHEMBL8065491 | 0.92 | MMP13 (0.77) | MMP13SLC22A8MMP3 | |
| SCHEMBL3809742 | 0.92 | MMP13 (0.75) | MMP13SLC22A8MMP3 | |
| SCHEMBL8056669 | 0.89 | MMP13 (0.74) | MMP13MMP3 | |
| SCHEMBL8069512 | 0.89 | MMP13 (0.74) | MMP13MMP3 | |
| SCHEMBL8077934 | 0.86 | MMP13 (0.80) | MMP13SLC22A8MMP3 | |
| SCHEMBL8072580 | 0.86 | MMP13 (0.78) | MMP13SLC22A8MMP3 | |
| SCHEMBL8068529 | 0.85 | MMP13 (0.75) | MMP13SLC22A8 | |
| SCHEMBL8068019 | 0.85 | MMP13 (0.85) | MMP13SLC22A8MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |