Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059596 | 0.88 | KMT2A (0.49) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL8058834 | 0.87 | KMT2A (0.50) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL8058833 | 0.86 | KMT2A (0.45) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL26197467 | 0.80 | SLC1A1 (0.48) | KMT2AHTTSLC1A1CA1CA2 | |
| SCHEMBL8058816 | 0.79 | KMT2A (0.43) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL10590595 | 0.79 | KMT2A (0.50) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL10594545 | 0.79 | KMT2A (0.50) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL22113526 | 0.79 | KMT2A (0.57) | KMT2AHTTSLC1A1NPC1MAPT | |
| SCHEMBL10563568 | 0.77 | KMT2A (0.55) | KMT2AHTTSLC1A1NPC1CA1 | |
| SCHEMBL1709343 | 0.76 | SLC1A1 (0.54) | SLC1A1CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015420-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012892-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |