Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.37 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.37 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058834 | 0.82 | KMT2A (0.50) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL8059596 | 0.81 | KMT2A (0.49) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL8058833 | 0.79 | KMT2A (0.45) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL8071200 | 0.79 | KMT2A (0.47) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL147688 | 0.76 | CTSL (0.46) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL122159 | 0.76 | CTSL (0.46) | KMT2AHTTMAPTMMP9MMP14 | |
| SCHEMBL10594545 | 0.74 | KMT2A (0.50) | KMT2AHTTMAPTSLC1A1NPC1 | |
| SCHEMBL10590595 | 0.74 | KMT2A (0.50) | KMT2AHTTMAPTSLC1A1NPC1 | |
| SCHEMBL22113526 | 0.74 | KMT2A (0.57) | KMT2AHTTMAPTSLC1A1NPC1 | |
| SCHEMBL8064380 | 0.73 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015412-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| EP-1015420-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AG (DE) | 2000-07-05 | — | — | EP | disclosed |
| WO-1999012892-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |
| WO-1999012885-A1 | SUBSTITUTED ALKENOIC ACIDS AND THEIR DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-18 | — | — | WO | disclosed |