Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28040820 | 0.96 | LMNA (0.36) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28040402 | 0.84 | ESR1 (0.41) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8079478 | 0.79 | LMNA (0.39) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL27886299 | 0.79 | LMNA (0.39) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL1028328 | 0.79 | LMNA (0.41) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL8079468 | 0.79 | LMNA (0.41) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL27886292 | 0.78 | SETD7 (0.34) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL28809673 | 0.76 | SETD7 (0.35) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL9065355 | 0.73 | LMNA (0.38) | LMNAMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL27870078 | 0.72 | NR1H2 (0.30) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376154-B2 | Bisindenyl derivative and method for its preparation | TARGOR GMBH (DE) | 2000-09-27 | — | — | EP | disclosed |
| EP-0692486-A2 | Bisindenyl derivative and process for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-01-17 | — | — | EP | disclosed |
| US-4985576-A | Bisindenyl derivative, and a process for the preparation thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-01-15 | — | — | US | disclosed |
| EP-0376154-A2 | Bisindenyl derivative and method for its preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-07-04 | — | — | EP | disclosed |