Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | RECQL | P46063 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068983 | 0.93 | ALDH1A1 (0.51) | CYP19A1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7831313 | 0.88 | SMN1; SMN2 (0.45) | CYP19A1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL8071479 | 0.87 | CYP19A1 (0.54) | CYP19A1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL5511589 | 0.87 | MAPT (0.44) | CYP19A1ALDH1A1UCHL1SMN1; SMN2MITF | |
| SCHEMBL7823456 | 0.86 | SMN1; SMN2 (0.44) | CYP19A1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7817398 | 0.86 | MAPT (0.43) | CYP19A1ALDH1A1MEN1KMT2AUCHL1 | |
| SCHEMBL7816184 | 0.85 | CYP19A1 (0.44) | CYP19A1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL7831187 | 0.85 | CYP19A1 (0.47) | CYP19A1ALDH1A1UCHL1SMN1; SMN2MITF | |
| SCHEMBL7827509 | 0.84 | MAOB (0.43) | CYP19A1ALDH1A1MEN1KMT2AMAPK1 | |
| SCHEMBL8071924 | 0.84 | CYP19A1 (0.48) | CYP19A1ALDH1A1MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |