Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | GPR183 | P32249 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068863 | 0.92 | GPR119 (0.53) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2898037 | 0.88 | GPR119 (0.54) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2898032 | 0.88 | GPR119 (0.54) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2899807 | 0.86 | GPR119 (0.53) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL8068864 | 0.86 | GPR119 (0.53) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2899804 | 0.86 | GPR119 (0.53) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2899006 | 0.86 | GPR119 (0.51) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL1923028 | 0.86 | GPR119 (0.52) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL1922732 | 0.86 | GPR119 (0.63) | GPR119KCNH2GPR183HRH3 | |
| SCHEMBL2895420 | 0.85 | GPR119 (0.51) | GPR119KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |