Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.65 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.63 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6593774 | 0.99 | DPP4 (0.64) | DPP4DPP8DPP9 | |
| SCHEMBL8268487 | 0.99 | DPP4 (0.64) | DPP4DPP8DPP9 | |
| SCHEMBL5100994 | 0.88 | DPP4 (0.51) | DPP4DPP8DPP9 | |
| SCHEMBL555779 | 0.85 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL4712769 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL4712767 | 0.83 | DPP4 (0.59) | DPP4DPP8DPP9 | |
| SCHEMBL15238181 | 0.82 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL4711726 | 0.82 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| SCHEMBL4711724 | 0.82 | DPP4 (0.49) | DPP4DPP8DPP9 | |
| Trifluoroacetic Acid SCHEMBL5103998 | 0.81 | DPP4 (0.45) | DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110949-A | A SERINE PROTEASE INHIBITOR TREATING NON-INSULIN-DEPENDENT DIABETES MELLITUS | NOVARTIS AG (CH) | 2000-08-29 | — | — | US | claimed |
| WO-2004111041-A1 | PYRROLIDINE, THIAZOLIDINE AND OXAZOLIDINE COMPOUNDS WHICH INHIBIT DIPEPTIDYL PEPTIDASE-IV (DPP) | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |
| US-6110949-A | A SERINE PROTEASE INHIBITOR TREATING NON-INSULIN-DEPENDENT DIABETES MELLITUS | NOVARTIS AG (CH) | 2000-08-29 | — | — | US | disclosed |