SCHEMBL8268487

SCHEMBL8268487

N#C[C@H]1CSCN1C(=O)CNC1CCCC1

nearest known ligand 0.64

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 17/20 0.64
DPP8 Q6V1X1 1/20 0.64
DPP9 Q86TI2 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8071679 0.99 DPP4 (0.65) DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL6593774 0.97 DPP4 (0.64) DPP4DPP8DPP9
SCHEMBL555779 0.86 DPP4 (0.49) DPP4DPP8DPP9
SCHEMBL5100994 0.86 DPP4 (0.51) DPP4DPP8DPP9
SCHEMBL4712769 0.84 DPP4 (0.59) DPP4DPP8DPP9
SCHEMBL4712767 0.84 DPP4 (0.59) DPP4DPP8DPP9
SCHEMBL15238181 0.83 DPP4 (0.49) DPP4DPP8DPP9
SCHEMBL4711724 0.83 DPP4 (0.49) DPP4DPP8DPP9
SCHEMBL4711726 0.83 DPP4 (0.49) DPP4DPP8DPP9
Hydrochloric Acid SCHEMBL1073331 0.82 DPP4 (0.48) DPP4DPP8DPP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006040625-A1 NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION GLENMARK PHARMACEUTICALS S.A. (US) 2006-04-20 WO disclosed