Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8067082 | 1.00 | KDM1A (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6699130 | 0.79 | GRIN2D (0.43) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL30715527 | 0.79 | IDO1 (0.44) | — | |
| SCHEMBL29833737 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL783223 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5271544 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL562559 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL3867845 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL8049751 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4168243 | 0.77 | ANPEP (0.42) | KDM1AGRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6127579-A | REACTING AN INDANYL ETHER UNDER BASIC CONDITIONS TO GIVE A NOVEL SUBSTANCE WHICH IS THE INDENYL ETHER DERIVATIVE AND HYDROLYZING THIS TO GIVE THE 1-INDANONE | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-10-03 | — | — | US | disclosed |
| EP-0968991-A1 | Method of manufacturing 1-indanone | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 2000-01-05 | — | — | EP | disclosed |
| EP-0658537-B1 | Method of producing cis-1-aminoindan-2-ol | ICHIKAWA GOSEI KAGAKU KK (JP) | 1999-03-31 | — | — | EP | disclosed |
| US-5760242-A | Method of producing a cis-oxazoline | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1998-06-02 | — | — | US | disclosed |
| US-5648534-A | Method of producing cis-1-aminoindan-2-ol | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0658537-A1 | Method of producing cis-1-aminoindan-2-ol | ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) | 1995-06-21 | — | — | EP | disclosed |