SCHEMBL562559

SCHEMBL562559

OC1Cc2ccccc2C1O

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.42
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
KDM1A O60341 4/20 0.41
CHRNB2 P17787 1/20 0.41
CHRNA4 P43681 1/20 0.41
HTR1A P08908 3/20 0.39
OPRM1 P35372 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL783223 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL29833737 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL19420453 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL4168243 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8049751 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL3867845 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5271544 1.00 ANPEP (0.42) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL5166344 0.94 ANPEP (0.39) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL6550318 0.83 KDM1A (0.48) ANPEPGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8077009 0.81 ACHE (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030022335-A1 Novel polypeptides and methods for their use UNIVERSITY OF IOWA RESEARCH FOUNDATION 2003-01-30 US claimed
US-6165777-A Process for the resolution of cis 1,2-indane diols using Pseudomonas putida ZENECA LIMITED (GB) 2000-12-26 US claimed
WO-2000037480-A1 NOVEL NAPHTHALENE DIOXYGENASE AND METHODS FOR THEIR USE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2000-06-29 WO claimed
EP-0784697-B1 BACTERIAL PROCESS FOR THE RESOLUTION OF RACEMIC CIS-DIOLS AVECIA LTD (GB) 2000-05-03 EP claimed
EP-0874059-A2 PROCESSES FOR PRODUCING INDANE DERIVATIVES NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-10-28 EP claimed
EP-0874059-A1 PROCESSES FOR PRODUCING INDANE DERIVATIVES NIPPON STEEL CHEMICAL CO., LTD. (JP) 1998-10-28 EP claimed
US-5811294-A Production of optically active 1,2-dihydroxyindance derivatives by asymetric assimilation ZENECA LIMITED (GB) 1998-09-22 US claimed
EP-0784697-A1 BACTERIAL PROCESS FOR THE RESOLUTION OF RACEMIC CIS-DIOLS ZENECA LIMITED (GB) 1997-07-23 EP claimed
WO-1996011282-A1 BACTERIAL PROCESS FOR THE RESOLUTION OF RACEMIC CIS-DIOLS ZENECA LIMITED (GB) 1996-04-18 WO claimed
EP-0658537-A1 Method of producing cis-1-aminoindan-2-ol ICHIKAWA GOSEI CHEMICAL CO., LTD. (JP) 1995-06-21 EP claimed
JP-8119891-A None JP disclosed
JP-9248195-A None JP disclosed
JP-10101603-A None JP disclosed
JP-11075888-A None JP disclosed
JP-7165647-A None JP disclosed
US-5373081-A Radiation transparent HOECHST AKTIENGESELLSCHAFT (DE) 1994-12-13 US disclosed
EP-0240568-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1989-11-15 EP disclosed
WO-1987001826-A1 SILVER HALIDE PHOTOGRAPHIC MATERIAL KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1987-03-26 WO disclosed
US-4559297-A DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1985-12-17 US disclosed
US-4182823-A ACID CHELATE OF BORIC ACID OR A DERIVATIVE THEREOF WITH A POLYHYDROXY COMPOUND NATIONAL STARCH AND CHEMICAL CORPORATION (US) 1980-01-08 US disclosed