Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.44 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21931632 | 1.00 | GPR84 (0.47) | GPR84FFAR1FFAR4ACE2MAPT | |
| SCHEMBL5983947 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4ACE2 | |
| SCHEMBL5983944 | 0.98 | GPR84 (0.44) | GPR84FFAR1FFAR4ACE2 | |
| SCHEMBL21931638 | 0.91 | PPARG (0.51) | FFAR1FFAR4MAPTPPARDALDH1A1 | |
| SCHEMBL5606209 | 0.83 | GPR84 (0.48) | GPR84FFAR1FFAR4ACE2MAPT | |
| SCHEMBL21931647 | 0.83 | GPR84 (0.48) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL26999624 | 0.83 | GPR84 (0.48) | GPR84FFAR1FFAR4MAPTLCK | |
| SCHEMBL10577135 | 0.83 | GPR84 (0.48) | GPR84FFAR1FFAR4ACE2MAPT | |
| SCHEMBL11867096 | 0.82 | FFAR4 (0.51) | GPR84FFAR1FFAR4PPARDALDH1A1 | |
| SCHEMBL20471673 | 0.82 | GPR84 (0.44) | GPR84FFAR1FFAR4ACE2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023466-A2 | MICROORGANISM GENOMICS, COMPOSITIONS AND METHODS RELATED THERETO | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2000-08-02 | — | — | EP | disclosed |
| WO-1999020799-A2 | MICROORGANISM GENOMICS, COMPOSITIONS AND METHODS RELATED THERETO | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1999-04-29 | — | — | WO | disclosed |