Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PON1 | P27169 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.57 |
| ▸ | HPGD | P15428 | 8/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.50 |
| ▸ | STS | P08842 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1102259 | 0.86 | CA9 (0.62) | PON1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8359458 | 0.81 | PON1 (0.61) | PON1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL30636721 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL67818 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL12181810 | 0.78 | PON1 (0.57) | PON1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24865358 | 0.77 | ALDH1A1 (0.72) | ALDH1A1KDM4EHPGDHSD17B10AKR1B1 | |
| SCHEMBL23056731 | 0.77 | PON1 (0.54) | PON1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL27523022 | 0.77 | ALDH1A1 (0.62) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL6503693 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10MAOA | |
| SCHEMBL17861315 | 0.75 | ALDH1A1 (0.60) | ALDH1A1KDM4EHPGDHSD17B10MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8293715-B2 | 10a-Azalide compound crosslinked at 10a- and 12-positions | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| EP-1036792-A1 | Novel fragrance compound | QUEST INTERNATIONAL B.V. (NL) | 2000-09-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110237784-A1 | 10A-AZALIDE COMPOUND CROSSLINKED AT 10A- AND 12-POSITIONS | DCLRE1A, AZI2, CHD9 | PON1 2964/4885ALDH1A1 2376/4885KDM4E 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.