Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17108819 | 0.83 | POLB (0.41) | PKMPOLBGAA | |
| SCHEMBL17108826 | 0.76 | POLB (0.36) | PKMPOLBGAA | |
| SCHEMBL21612673 | 0.72 | KDM4E (0.33) | GAAKDM4EHSD17B10MEN1MAPT | |
| SCHEMBL5257107 | 0.72 | — | — | |
| SCHEMBL1535216 | 0.71 | POLB (0.47) | PKMPOLBGAANOS1CA12 | |
| SCHEMBL18704862 | 0.71 | POLB (0.33) | PKMPOLBGAA | |
| SCHEMBL7160904 | 0.71 | POLB (0.38) | PKMPOLBGAAKDM4EALDH1A1 | |
| SCHEMBL28225029 | 0.71 | POLB (0.38) | PKMPOLBGAA | |
| SCHEMBL27325295 | 0.68 | POLB (0.33) | PKMPOLBGAA | |
| SCHEMBL21612663 | 0.68 | GAA (0.31) | GAAKDM4EHSD17B10MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000128867-A | 1-SULFONYLPYRAZOLE DERIVATIVE AND ITS PRODUCTION | UBE IND LTD | 2000-05-09 | — | — | JP | disclosed |