Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.51 |
| ▸ | MC3R | P41968 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.51 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.51 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.51 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.51 |
| ▸ | PDE4A | P27815 | 5/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8952269 | 1.00 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL8076046 | 1.00 | ADORA2B (0.51) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL9295135 | 0.96 | ADORA2B (0.52) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL11213748 | 0.85 | ADORA2B (0.58) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL6773714 | 0.85 | ADORA2B (0.46) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL6773717 | 0.85 | ADORA2B (0.46) | ADORA2BADORA2AACHEPIK3CDPOLB | |
| SCHEMBL7994674 | 0.82 | ADORA2B (0.62) | ADORA2BADORA2AACHEPDE4APDE4B | |
| SCHEMBL7994672 | 0.82 | ADORA2B (0.62) | ADORA2BADORA2AACHEPDE4APDE4B | |
| SCHEMBL8431062 | 0.81 | ADORA2B (0.60) | ADORA2BADORA2AACHEPDE4APDE4B | |
| SCHEMBL8431058 | 0.81 | ADORA2B (0.60) | ADORA2BADORA2AACHEPDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121270-A | N-(EPOXYALKYL)XANTHINE DERIVATIVES WHICH MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI | CELL THERAPEUTICS, INC. (US) | 2000-09-19 | — | — | US | disclosed |
| US-5866576-A | COMPOUNDS THAT ACT AS DRUGS ON THE CELLULAR AND BIOCHEMICAL LEVEL TO MODULATE CELLULAR RESPONSES TO NOXIOUS, PRO-INFLAMMATORY STIMULI. | CELL THERAPEUTICS, INC. (US) | 1999-02-02 | — | — | US | disclosed |
| US-5859017-A | PREVENTING OR TREATING ALLERGIES; INHIBITING INTRACELLULAR GENERATION OF PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. (US) | 1999-01-12 | — | — | US | disclosed |
| US-5521315-A | Olefin substituted long chain compounds | CELL THERAPEUTICS, INC. (US) | 1996-05-28 | — | — | US | disclosed |
| US-5354756-A | Inhibiting second messenger pathway | CELL THERAPEUTICS, INC. (US) | 1994-10-11 | — | — | US | disclosed |