Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.47 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.47 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.47 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077923 | 0.92 | THRA (0.49) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8070949 | 0.92 | MAPT (0.45) | CSNK1A1CSNK1DPRKCDPAK1CAMK2B | |
| SCHEMBL8078000 | 0.91 | THRA (0.51) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8072702 | 0.89 | THRA (0.53) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8062704 | 0.89 | THRA (0.53) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8062722 | 0.89 | THRA (0.53) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8072540 | 0.89 | THRA (0.53) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL22700920 | 0.86 | KDM4E (0.53) | L3MBTL1MAPTHPGDNPSR1ALDH1A1 | |
| SCHEMBL5270852 | 0.86 | THRA (0.57) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D | |
| SCHEMBL8062361 | 0.86 | THRA (0.46) | CYP1A2CYP2C9CYP2C19CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |