SCHEMBL8072391

SCHEMBL8072391

Cc1nc2cc(S(=O)(=O)N3CCOCC3)ccc2n1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
GAA P10253 3/20 0.61
KMT2A Q03164 3/20 0.61
KDM4E B2RXH2 3/20 0.61
HSD17B10 Q99714 3/20 0.61
MEN1 O00255 2/20 0.61
HPGD P15428 2/20 0.61
LMNA P02545 2/20 0.57
SMN1; SMN2 Q16637 3/20 0.56
TSHR P16473 3/20 0.56
HTT P42858 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
POLB P06746 2/20 0.53
CASP1 P29466 2/20 0.53
MAPT P10636 2/20 0.53
THRB P10828 1/20 0.53
ALOX15 P16050 1/20 0.53
ALOX12 P18054 1/20 0.53
MAPK1 P28482 1/20 0.53
PTPN7 P35236 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10953522 0.88 SMN1; SMN2 (0.70) ALDH1A1KMT2AKDM4EHSD17B10MEN1
SCHEMBL8380209 0.81 KMT2A (0.60) ALDH1A1GAAKMT2AKDM4EHSD17B10
SCHEMBL11558680 0.76 CA12 (0.52) ALDH1A1GAAKMT2AKDM4EMEN1
SCHEMBL31195035 0.75 CA12 (0.51) ALDH1A1GAAKMT2AKDM4EMEN1
SCHEMBL3728185 0.75 CA1 (0.71) ALDH1A1GAAKMT2AKDM4EMEN1
SCHEMBL8265452 0.74 SMN1; SMN2 (0.53) ALDH1A1GAAKMT2AKDM4EHSD17B10
SCHEMBL12757098 0.73 SMN1; SMN2 (0.75) ALDH1A1GAAKMT2AKDM4EHSD17B10
SCHEMBL29483506 0.73 CASP3 (0.57) ALDH1A1GAAKMT2AKDM4EHSD17B10
SCHEMBL11558330 0.72 CYP1A2 (0.52) ALDH1A1GAAKMT2AKDM4EMEN1
SCHEMBL17702674 0.72 GAA (0.64) ALDH1A1GAAKMT2AKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6093527-A INCREASE IN SENSITIVITY WHILE MAINTAINING LOW FOG AND EXCELLENT STORAGE STABILITY AT HIGH TEMPERATURE AND HUMIDITY; SPECTRALLY SENSITIZE A SHORT WAVELENGTH REGION OF 530 TO 540 NM OF GREEN LIGHT KONICA CORPORATION (JP) 2000-07-25 US disclosed