Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.44 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.39 |
| ▸ | TACR2 | P21452 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3745225 | 1.00 | TAAR1 (0.50) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL8071279 | 1.00 | TAAR1 (0.50) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL8062227 | 1.00 | TAAR1 (0.50) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL5795842 | 1.00 | TAAR1 (0.50) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL8070958 | 1.00 | TAAR1 (0.50) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL8071396 | 0.98 | TAAR1 (0.52) | TAAR1HTR2ASIRT2HMOX1THRA | |
| SCHEMBL80599 | 0.90 | TAAR1 (0.54) | TAAR1HTR2ASIRT2HMOX1 | |
| SCHEMBL15583726 | 0.90 | TAAR1 (0.59) | TAAR1HTR2AHMOX1HSP90AA1ESR1 | |
| SCHEMBL134452 | 0.90 | TAAR1 (0.59) | TAAR1HTR2AHMOX1HSP90AA1ESR1 | |
| SCHEMBL9670640 | 0.90 | THRA (0.50) | HTR2ATHRATHRBHDAC1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |