Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 5/20 | 0.63 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072865 | 1.00 | ADRB3 (0.63) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8073035 | 0.89 | ADRB3 (0.65) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8073030 | 0.89 | ADRB3 (0.65) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7104879 | 0.87 | ADRB3 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7104876 | 0.87 | ADRB3 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8085291 | 0.84 | ADRB2 (0.68) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL8085293 | 0.84 | ADRB2 (0.68) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7107117 | 0.82 | ADRB3 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7107114 | 0.82 | ADRB3 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| Acetic Acid SCHEMBL7107390 | 0.81 | ADRB3 (0.63) | ADRB3ADRB2LMNAHIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043308-A1 | PHENYLAMINOALKYLCARBOXYLIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2000-10-11 | — | — | EP | disclosed |