Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | THRB | P10828 | 8/20 | 0.53 |
| ▸ | THRA | P10827 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 2/20 | 0.52 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.52 |
| ▸ | TACR2 | P21452 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.52 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077513 | 1.00 | TSHR (0.58) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8062204 | 1.00 | TSHR (0.58) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8076182 | 1.00 | TSHR (0.58) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8072343 | 0.98 | TSHR (0.54) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8071283 | 0.92 | TSHR (0.52) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8062478 | 0.92 | TSHR (0.52) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8062042 | 0.92 | TSHR (0.52) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8072063 | 0.92 | TSHR (0.52) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8063254 | 0.92 | THRB (0.55) | TSHRTHRBTHRAMEN1KMT2A | |
| SCHEMBL8072141 | 0.90 | TSHR (0.48) | TSHRTHRBTHRAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |