Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 20/20 | 0.78 |
| ▸ | MMP3 | P08254 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069554 | 0.93 | MMP13 (0.78) | MMP13MMP3SLC22A8 | |
| SCHEMBL8070799 | 0.90 | MMP13 (0.73) | MMP13MMP3SLC22A8 | |
| SCHEMBL8055443 | 0.89 | MMP13 (0.76) | MMP13MMP3SLC22A8 | |
| SCHEMBL8071757 | 0.89 | MMP13 (0.76) | MMP13MMP3SLC22A8 | |
| SCHEMBL3688006 | 0.89 | MMP13 (0.76) | MMP13MMP3SLC22A8 | |
| SCHEMBL8073489 | 0.88 | MMP13 (1.00) | MMP13MMP3SLC22A8 | |
| SCHEMBL3691634 | 0.88 | MMP13 (0.76) | MMP13MMP3SLC22A8 | |
| SCHEMBL3691632 | 0.88 | MMP13 (0.76) | MMP13MMP3SLC22A8 | |
| SCHEMBL8071238 | 0.87 | MMP13 (0.77) | MMP13MMP3SLC22A8 | |
| SCHEMBL8066195 | 0.86 | MMP13 (0.88) | MMP13MMP3SLC22A8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016498-A1 | PYRIMIDINE AND PYRIDINE DERIVATIVES AND THEIR PHARMACEUTICAL USE AND COMPOSITIONS | PFIZER INC. (US) | 2009-02-05 | — | — | WO | disclosed |