Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7827679 | 0.93 | UCHL1 (0.40) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL27386727 | 0.92 | PTGER4 (0.38) | POLBMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL7827030 | 0.91 | UCHL1 (0.42) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL7817162 | 0.90 | UCHL1 (0.39) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL7827496 | 0.90 | MAPT (0.39) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL5515660 | 0.90 | UCHL1 (0.41) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL8057419 | 0.88 | SLC5A1 (0.40) | POLBRXFP1MAPTKMT2AALDH1A1 | |
| SCHEMBL8071411 | 0.87 | UCHL1 (0.39) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL5509234 | 0.85 | UCHL1 (0.38) | UCHL1POLBRXFP1MAPTKMT2A | |
| SCHEMBL8067099 | 0.85 | UCHL1 (0.38) | UCHL1POLBRXFP1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |