SCHEMBL8073685

SCHEMBL8073685

CCOCn1c(Oc2ccccc2)c(CC)c(=O)[nH]c1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NTRK1 P04629 2/20 0.37
NTRK3 Q16288 2/20 0.37
NTRK2 Q16620 2/20 0.37
DAO P14920 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DRD1 P21728 2/20 0.36
HPGD P15428 2/20 0.36
IGF1R P08069 1/20 0.36
FGFR1 P11362 1/20 0.36
UPP1 Q16831 1/20 0.35
SIRT2 Q8IXJ6 1/20 0.35
SIRT1 Q96EB6 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7037489 0.84 SMN1; SMN2 (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2DRD1
SCHEMBL8058413 0.82 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ANTRK1NTRK3
SCHEMBL8067219 0.80 ALDH1A1 (0.55) ALDH1A1MEN1KMT2ADAOHPGD
SCHEMBL8389080 0.80 NTRK1 (0.37) ALDH1A1MEN1KMT2ANTRK1NTRK3
SCHEMBL598947 0.78 ALDH1A1 (0.45) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL1687625 0.76 MAPT (0.33) ALDH1A1NTRK1NTRK3NTRK2HPGD
SCHEMBL1443402 0.76 ALDH1A1 (0.43) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL8069213 0.76 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ADAOSMN1; SMN2
SCHEMBL599846 0.76 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ASMN1; SMN2HPGD
SCHEMBL6086864 0.74 HPGD (0.44) ALDH1A1MEN1KMT2AHPGDSIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136815-A VIRICIDES FOR TREATMENT OF AIDS KOREA RESEARCH INST. OF CHEM. TECH. (KR) 2000-10-24 US disclosed