Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8071479 | 0.93 | CYP19A1 (0.54) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL8068983 | 0.87 | ALDH1A1 (0.51) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL7815561 | 0.85 | POLB (0.46) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL7829087 | 0.85 | POLB (0.48) | CYP19A1UCHL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8057540 | 0.83 | HSD17B10 (0.44) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL7827011 | 0.82 | POLB (0.50) | RECQLUCHL1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8057633 | 0.81 | POLB (0.44) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL8071978 | 0.81 | HSD17B10 (0.44) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL8057862 | 0.81 | HSD17B10 (0.44) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 | |
| SCHEMBL8068083 | 0.81 | AKR1C3 (0.48) | CYP19A1RECQLUCHL1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |