Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 13/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.32 |
| ▸ | TPH1 | P17752 | 1/20 | 0.31 |
| ▸ | TPH2 | Q8IWU9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059927 | 0.81 | ATP4A (0.42) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8061865 | 0.81 | ATP4A (0.42) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8073957 | 0.80 | ATP4A (0.42) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8074411 | 0.76 | NPC1 (0.40) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8060015 | 0.76 | PDE10A (0.40) | OPRL1EGLN1FGFR1FGFR2FGFR3 | |
| SCHEMBL8074093 | 0.72 | ATP4A (0.44) | OPRL1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL8069345 | 0.71 | CYP11B1 (0.38) | — | |
| SCHEMBL8071077 | 0.71 | ATP4A (0.40) | OPRL1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL8071076 | 0.70 | ATP4A (0.39) | OPRL1FGFR1FGFR2FGFR3KDR | |
| SCHEMBL8059765 | 0.69 | OPRL1 (0.41) | OPRL1FGFR1FGFR2FGFR3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |