⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520065 | 1.00 | — | — | |
| SCHEMBL25600153 | 1.00 | — | — | |
| Trifluoroacetic Acid SCHEMBL5319837 | 0.85 | CA1 (0.40) | — | |
| SCHEMBL15726596 | 0.84 | CA1 (0.38) | — | |
| SCHEMBL4430069 | 0.84 | CA1 (0.45) | — | |
| SCHEMBL12951611 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL807405 | 0.82 | ALDH1A1 (0.43) | — | |
| SCHEMBL6385908 | 0.81 | CA1 (0.39) | — | |
| SCHEMBL882111 | 0.80 | — | — | |
| SCHEMBL12072072 | 0.80 | CA1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102372674-A | Synthesis method for pharmaceutical intermediate 3-formyl-4-halogeno pyrazole | WUXI APPTEC CO LTD | 2012-03-14 | — | — | CN | claimed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | claimed |
| JP-7228895-A | — | — | None | — | — | JP | disclosed |
| US-20250177539-A1 | ER DEGRADERS AND USES THEREOF | ASTRAZENECA AB (SE) | 2025-06-05 | — | — | US | disclosed |
| EP-4392420-A1 | HPK1 DEGRADERS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME | BIOFRONT LTD (KY) | 2024-07-03 | — | — | EP | disclosed |
| CN-118267729-A | System for producing 4-chlorobutyrate methyl ester by thionyl chloride method and control method | 江西世龙实业股份有限公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-117908324-A | Negative photosensitive resin composition for high refractive index patterning | 罗门哈斯电子材料韩国有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-111868051-B | Aminopyrimidine derivatives as CTPS1 inhibitors | 斯泰普制药股份公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117343049-A | Rho-related protein kinase inhibitor, pharmaceutical composition containing Rho-related protein kinase inhibitor, and preparation method and application of Rho-related protein kinase inhibitor | 北京泰德制药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-110582489-B | Rho-related protein kinase inhibitor, pharmaceutical composition containing Rho-related protein kinase inhibitor, and preparation method and application of Rho-related protein kinase inhibitor | 北京泰德制药股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-20230125751-A1 | METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS | GILEAD SCIENCES, INC. | 2023-04-27 | — | — | US | disclosed |
| CN-1717625-A | Template | INGENIA TECHNOLOGY LTD (VG) | 2006-01-04 | — | — | CN | disclosed |
| US-20040181094-A1 | Transition metal oxo complexes as catalysts of synthetic processes involving alkyne reactants | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-09-16 | — | — | US | disclosed |
| EP-1304325-A1 | 5-(M-CYANOBENZYLAMINO)PYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-04-23 | — | — | EP | disclosed |
| CN-1290249-A | Aminoguanidine hydrazone derivatives, process for producing the same and drugs thereof | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-04-04 | — | — | CN | disclosed |
| EP-0379691-B2 | Process for preparing unsaturated carboxylic acid or ester thereof | MITSUBISHI GAS CHEMICAL CO (JP) | 2001-01-03 | — | — | EP | disclosed |
| JP-H07228895-A | SOLVENT COMPOSITION | NITTO CHEM IND CO LTD | 1995-08-29 | — | — | JP | disclosed |
| US-5250729-A | Process for preparing unsaturated carboxylic acid or ester thereof | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-4520209-A | Process for cyclizing upsilon-chlorocarboxylic acids | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-05-28 | — | — | US | disclosed |
| US-4156785-A | FROM AN UNSATURATED HALOGEN COMPOUND, CARBON MONOXIDE AND AN ALKALI METAL ALCOHOLATE USING NICKEL OR COBALT CARBONYL AS CATALYST | DYNAMIT NOBEL AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |