Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | FABP2 | P12104 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278303 | 0.87 | KMT2A (0.47) | KMT2AMEN1MAPTCYP2C9BACE1 | |
| SCHEMBL14471688 | 0.80 | BACE1 (0.50) | KMT2AMEN1BACE1HPGDALDH1A1 | |
| SCHEMBL11640483 | 0.79 | KMT2A (0.51) | KMT2AATMCYP11B1CYP11B2MEN1 | |
| SCHEMBL1443906 | 0.79 | SLC6A4 (0.39) | KMT2AMEN1MAPTPTGS2PTGS1 | |
| SCHEMBL27878592 | 0.78 | TOP2A (0.52) | KMT2AMEN1MAPTCYP2C9TSHR | |
| SCHEMBL22414012 | 0.78 | BACE1 (0.45) | KMT2AMEN1MAPTCYP2C9BACE1 | |
| SCHEMBL30986702 | 0.77 | CES2 (0.43) | KMT2AATMCYP11B1CYP11B2MEN1 | |
| SCHEMBL30910940 | 0.77 | CES2 (0.43) | KMT2AATMCYP11B1CYP11B2MEN1 | |
| SCHEMBL6566037 | 0.77 | CES2 (0.43) | KMT2AATMCYP11B1CYP11B2MEN1 | |
| SCHEMBL9193862 | 0.76 | MEN1 (0.52) | KMT2AMEN1MAPTCYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |