Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 11/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 8/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.32 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ABHD11 | Q8NFV4 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.31 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077925 | 0.92 | DAGLA (0.32) | DAGLAABHD6HCRTR2PRMT5WDR77 | |
| SCHEMBL8079946 | 0.91 | DAGLB (0.34) | DAGLAABHD6HCRTR2PRMT5WDR77 | |
| SCHEMBL8144465 | 0.87 | DAGLA (0.33) | DAGLAABHD6HCRTR2PDCD1CD274 | |
| SCHEMBL7909447 | 0.87 | DAGLA (0.33) | DAGLAABHD6HCRTR2PRMT5WDR77 | |
| SCHEMBL8146211 | 0.85 | KDM4E (0.47) | HPGDNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL8138501 | 0.85 | KDM4E (0.38) | DAGLAABHD6HCRTR2HPGDNPC1 | |
| SCHEMBL8136076 | 0.84 | KDM4E (0.38) | DAGLAABHD6HCRTR2HPGDHCRTR1 | |
| SCHEMBL8145765 | 0.84 | KDM4E (0.40) | DAGLAABHD6HCRTR2HPGDABHD11 | |
| SCHEMBL8138505 | 0.83 | DAGLA (0.35) | DAGLAABHD6HCRTR2PDCD1CD274 | |
| SCHEMBL8152792 | 0.83 | DAGLA (0.38) | DAGLAHPGDDAGLBKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009003997-A1 | IMIDAZO [1, 2-C] PYRIMIDIN-2-YLMETHYLPIPERIDINES AS OREXIN RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2009-01-08 | — | — | WO | disclosed |