Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIP5K1C | O60331 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL807635 | 0.73 | PIP5K1C (0.48) | PIP5K1C | |
| SCHEMBL806815 | 0.72 | PIP5K1C (0.51) | PIP5K1C | |
| SCHEMBL807205 | 0.72 | PIP5K1C (0.51) | PIP5K1C | |
| SCHEMBL807633 | 0.66 | NTRK1 (0.47) | PIP5K1C | |
| SCHEMBL21255668 | 0.65 | CREBBP (0.46) | — | |
| SCHEMBL19413417 | 0.61 | CREBBP (0.58) | — | |
| SCHEMBL8959410 | 0.60 | KDM4E (0.46) | — | |
| SCHEMBL22474043 | 0.60 | CREBBP (0.62) | — | |
| SCHEMBL1918845 | 0.60 | KDM4E (0.61) | — | |
| SCHEMBL8959413 | 0.59 | KDM4E (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |