Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | PPARD | Q03181 | 5/20 | 0.50 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 3/20 | 0.45 |
| ▸ | CES1 | P23141 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10931635 | 0.96 | ALDH1A1 (0.64) | ALDH1A1TSHRTP53PPARDZDHHC7 | |
| SCHEMBL10937797 | 0.85 | ALDH1A1 (0.48) | ALDH1A1TSHRTP53PPARDZDHHC7 | |
| SCHEMBL21183320 | 0.84 | TSHR (0.75) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL1138766 | 0.84 | TSHR (0.75) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL1339298 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL517004 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL3674715 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL69357 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTP53PPARDFFAR4 | |
| SCHEMBL825395 | 0.83 | — | — | |
| SCHEMBL177408 | 0.83 | TSHR (1.00) | ALDH1A1TSHRTP53PPARDFFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041889-A1 | SURFACE-MODIFIED CELLULOSE AS LOW CALORIE FLOUR REPLACEMENTS | NABISCO, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| US-5906852-A | FOODS WITH CELLULOSE SURFACES AND ACYLATED WITH ALIPHATIC ACIDS | NABISCO, INC. (US) | 1999-05-25 | — | — | US | disclosed |
| WO-1999022599-A1 | SURFACE-MODIFIED CELLULOSE AS LOW CALORIE FLOUR REPLACEMENTS | NABISCO, INC. (US) | 1999-05-14 | — | — | WO | disclosed |
| US-5550161-A | COMPOUNDS WHICH CHELATE IRON AND ALUMINUM IONS; TREATMENT OF VARIOUS ANEMIAS, HEMOSIDEROSIS, ALZHEIMER*S DISEASE | ORAL-D (US) | 1996-08-27 | — | — | US | disclosed |
| WO-1992020227-A1 | SUBSTITUTED ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE | ORAL-D (US) | 1992-11-26 | — | — | WO | disclosed |
| US-5047421-A | Treating trivalent metal overload conditions in humans | ORAL-D (US) | 1991-09-10 | — | — | US | disclosed |
| US-5015664-A | Orally effective ion chelators related to deferoxamine | ORAL D (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0171414-B1 | ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE | ORAL D (US) | 1990-09-26 | — | — | EP | disclosed |
| US-4684482-A | DEFEROXAMINE DERIVATIVES | ORAL-D (L.P.) (US) | 1987-08-04 | — | — | US | disclosed |
| US-4671901-A | DIFEROXAMINE DERIVATIVES FOR REDUCTION OF METAL ION TUSSUE OV ERLOAD | ORAL-D (US) | 1987-06-09 | — | — | US | disclosed |
| EP-0171414-A1 | ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE. | ORAL D (US) | 1986-02-19 | — | — | EP | disclosed |
| WO-1985003290-A1 | ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE | ORAL-D (US) | 1985-08-01 | — | — | WO | disclosed |