Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR1 | P30872 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.51 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059127 | 0.88 | HDAC3 (0.49) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL8059137 | 0.86 | MAPT (0.47) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13807191 | 0.86 | SSTR1 (0.62) | SSTR1HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL29644567 | 0.80 | MAPT (0.55) | HDAC1HDAC3HDAC2HDAC10HDAC11 | |
| SCHEMBL29025531 | 0.79 | HDAC3 (0.54) | SSTR1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL26902843 | 0.79 | HDAC3 (0.54) | SSTR1HDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL8069944 | 0.78 | HDAC1 (0.57) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL21158887 | 0.77 | SSTR1 (0.61) | SSTR1 | |
| SCHEMBL3952877 | 0.77 | SIRT2 (0.72) | SIRT2SIRT1SIRT3 | |
| SCHEMBL3952882 | 0.77 | SIRT2 (0.72) | SIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |