Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 10/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 8/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 5/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059127 | 0.87 | HDAC3 (0.49) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8075112 | 0.86 | SSTR1 (0.56) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8069944 | 0.76 | HDAC1 (0.57) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8079292 | 0.74 | HDAC1 (0.53) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3952882 | 0.74 | SIRT2 (0.72) | SIRT2SIRT1SIRT3TGM2SIRT5 | |
| SCHEMBL3952877 | 0.74 | SIRT2 (0.72) | SIRT2SIRT1SIRT3TGM2SIRT5 | |
| SCHEMBL3953097 | 0.73 | SIRT2 (0.73) | SIRT2SIRT1SIRT3SIRT5FOLH1 | |
| SCHEMBL3953099 | 0.73 | SIRT2 (0.73) | SIRT2SIRT1SIRT3SIRT5FOLH1 | |
| SCHEMBL8079294 | 0.73 | HDAC6 (0.49) | MAPTHDAC3HDAC4HDAC1HDAC7 | |
| Trifluoroacetic Acid SCHEMBL15671472 | 0.72 | HDAC1 (0.44) | MAPTHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |